University of Liège
Human sleep-wake regulation, cognition, Alzheimer’s disease, electrophysiology, neuroimaging
Background. Amyloid beta plaque brain accumulation is a central feature of the pathophysiology of Alzheimer’s disease. Amyloid plaque formation starts years prior to cognitive symptom onset and may be associated with more prominent age-related degradation of sleep-wake regulation. We want to isolate features of sleep-wake brain regulation that are associated with Amyloid beta deposits assessed via PET scans.
The candidate will participate to acquisitions and analyses of data obtained in strictly controlled chronobiology protocols. He will use a wide variety of approaches including neuropsychological testing, EEG, TMS, MRI, and PET (analyses only for the latter).
Qualifications and requirements. Candidates can have a MSc in any disciplines related to the topics of the call: biomedical sciences, (neuro)psychology, biology, (bio)chemistry, biostatistics. They should be interested in the brain mechanisms of cognition and sleep and wakefulness regulation in aging.
Candidates could have skills and experience in one or more of the following topics: acquisition/analysis of MRI, DWI, EEG data; TMS; neuropsychological assessments; running constant routine protocols.
Speaking French is considered as a strength (for interactions with study participants) but candidates willing to learn French during the PhD training are also strongly encourage to apply.
Supervisor. The PhD bursary will be mainly supervised by Dr. Gilles Vandewalle and Dr. Fabienne Collette at the GIGA – Cyclotron Research Centre / In Vivo Imaging.
Our team has direct access to research-dedicated neuroimaging and electrophysiology equipment including a 3T MRI scanner (and a 7T MR scanner from 2018), a PET scanner, five bedrooms for full polysomnography recordings and neuropsychological testing, a neuro-navigated TMS-EEG apparatus, and a growing database of participants included in chronobiology protocols.
Within the GIGA Graduate schoold, PhD bursaries will have the opportunity to follow specific training and improve their skills in relation to the project topics.
The PhD bursaries are advertised for 2 years, extendable to 2 more years, and start on October 1st 2017. Monthly salary of bursary will be provided upon request and follows Belgian regulations.
Applicants are invited to respond as soon as possible and no later than July 7th, 2017, by submitting a curriculum vitae (including publication list if applicable), a one‐page summary of research interests and expertise, and names and contact details of two referees to firstname.lastname@example.org
GIGA-R – Cyclotron Research Centre/In Vivo Imaging Unit B30, 8 Allée du VI Août, Quartier Agora, B-4000 Liège, Belgium Tel +32 4 366 23 16 Fax +32 4 366 29 46 www.giga.ulg.ac.be/crc – www.giga.ulg.ac.be/sleep